Rsv virus detection
Learn more about laboratory tests, reference ranges, and understanding results. If you have RSV symptoms, but are otherwise in good health, your health care provider probably won't order RSV testing. Most healthy adults and children with RSV will get better in weeks. Your provider may recommend over-the-counter medicines to relieve your symptoms. The information on this site should not be used as a substitute for professional medical care or advice. Contact a health care provider if you have questions about your health.
What is an RSV test? Other names: respiratory syncytial antibody test, RSV rapid detection. What is it used for? Why do I need an RSV test? These include: Fever Wheezing Severe coughing Breathing faster than normal, especially in infants Trouble breathing Skin that turns blue. What happens during an RSV test? There are a few different types of RSV testing: Nasal aspirate. Philadelphia, Pa: W. Saunders; Landry M L. Rapid viral diagnosis.
Manual of clinical laboratory immunology. Washington, D. C: ASM Press; Validation of respiratory syncytial virus enzyme immunoassay and shell vial assay results. Viral lower respiratory tract infections in Istanbul, Turkey. Pediatr Infect Dis J.
Support Center Support Center. Therefore, accurate and timely laboratory testing is needed to impact clinical management. There are now multiple rapid, low-complexity, commercially available assays for RSV. These tests present significant performance advantages compared to older antigen detection tests. Respiratory syncytial virus infections in pediatric transplant recipients: a Canadian Paediatric Surveillance Program study.
Pediatr Transplant 19 — Efficacy of oral ribavirin in lung transplant patients with respiratory syncytial virus lower respiratory tract infection. J Heart Lung Transplant 28 — Oral ribavirin for respiratory syncytial virus infection after lung transplantation: efficacy and cost-efficiency.
J Heart Lung Transplant 34 — Respiratory syncytial virus infection in recipients of allogeneic stem-cell transplantation: a retrospective study of the incidence, clinical features, and outcome. Transplantation 88 — J Pediatr — Economic impact of respiratory syncytial virus-related illness in the US: an analysis of national databases.
Pharmacoeconomics 22 — Detection of respiratory syncytial virus in adults with chronic obstructive pulmonary disease. Community-acquired pneumonia requiring hospitalization among U.
Hislop AA. Airway and blood vessel interaction during lung development. J Anat — A passive quantitative measurement of airway resistance using depth data.
Goetzl EJ. Mediators of immediate hypersensitivity derived from arachidonic acid. The mechanics of airway narrowing in asthma. Am Rev Respir Dis — Hennessy AV. An attempt to demonstrate a viral etiology for chronic bronchitis. Am Rev Respir Dis 86 — Semin Respir Infect 3 — Monto AS. Epidemiology of respiratory viruses in persons with and without asthma and COPD. Mechanisms of airway narrowing and hyperresponsiveness in viral respiratory tract infections.
Viruses as co-factors for the initiation or exacerbation of lung fibrosis. Fibrogenesis Tissue Repair 1 Latent herpesvirus infection augments experimental pulmonary fibrosis.
Lung function of preterm infants before and after viral infections. Eur J Pediatr — ILdependent type 2 inflammation during rhinovirus-induced asthma exacerbations in vivo. IL, an interleukinlike cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity 23 — Risk factors for acute respiratory infection in the Australian community. PLoS One 9 :e Factors associated with increased risk of progression to respiratory syncytial virus-associated pneumonia in young Kenyan children.
Trop Med Int Health 13 — Risk factors for severe respiratory syncytial virus infection leading to hospital admission in children in the Western Region of The Gambia. Int J Epidemiol 28 — Incidence and risk factors for respiratory syncytial virus and human metapneumovirus infections among children in the remote highlands of Peru.
PLoS One 10 :e Risk factors for hospitalization due to respiratory syncytial virus infection among infants in the Basque Country, Spain. Epidemiol Infect — Impact of respiratory virus infections on persons with chronic underlying conditions. JAMA — Risks and prevention of severe RS virus infection among children with immunodeficiency and Down's syndrome.
J Infect Chemother 20 — Fixler DE. Respiratory syncytial virus infection in children with congenital heart disease: a review. Pediatr Cardiol 17 — American Academy of Pediatrics Committee on Infectious Diseases: ribavirin therapy of respiratory syncytial virus. Pediatrics 79 — Risk factors associated with death in patients with severe respiratory syncytial virus infection.
J Microbiol Immunol Infect 49 — Geevarghese B, Weinberg A. Cell-mediated immune responses to respiratory syncytial virus infection: magnitude, kinetics, and correlates with morbidity and age. Hum Vaccin Immunother 10 — Reduced interferon-gamma expression in peripheral blood mononuclear cells of infants with severe respiratory syncytial virus disease. Local interferon-gamma levels during respiratory syncytial virus lower respiratory tract infection are associated with disease severity.
Moderate local and systemic respiratory syncytial virus-specific T-cell responses upon mild or subclinical RSV infection. J Med Virol 70 — Parasitic central nervous system infections in immunocompromised hosts: malaria, microsporidiosis, leishmaniasis, and African trypanosomiasis.
Clin Infect Dis 42 — Life-threatening infection in transplant recipients. Crit Care Clin 29 — Kumar D, Humar A. Respiratory viral infections in transplant and oncology patients. Infect Dis Clin North Am 24 — Differential effects of tacrolimus versus sirolimus on the proliferation, activation and differentiation of human B cells. Effects of immunosuppressive drugs on purified human B cells: evidence supporting the use of MMF and rapamycin. Transplantation 86 — Effect of infectious diseases on outcome after heart transplant.
Mayo Clin Proc 83 — Respiratory syncytial virus and other respiratory viral infections in older adults with moderate to severe influenza-like illness. High morbidity and mortality in adults hospitalized for respiratory syncytial virus infections. Clin Infect Dis 57 — Relationship of serum antibody to risk of respiratory syncytial virus infection in elderly adults. Humoral and mucosal immunity in protection from natural respiratory syncytial virus infection in adults.
Regulation of cytokine production in aging: use of recombinant cytokines to upregulate mitogen-stimulated spleen cells. Mech Ageing Dev 93 — J Immunol — Immunoregulation in aging. Ann N Y Acad Sci — Isolation and characterisation of potential respiratory syncytial virus receptor s on epithelial cells. Microbes Infect 5 — Respiratory syncytial virus uses CX3CR1 as a receptor on primary human airway epithelial cultures. PLoS Pathog 11 :e CX3C chemokine mimicry by respiratory syncytial virus G glycoprotein.
Nat Immunol 2 — EGFR interacts with the fusion protein of respiratory syncytial virus strain and mediates infection and mucin expression. PLoS Pathog 12 :e Nat Immunol 1 — Toll-like receptor 4-mediated activation of p38 mitogen-activated protein kinase is a determinant of respiratory virus entry and tropism. J Virol 84 — Blocking intercellular adhesion molecule-1 on human epithelial cells decreases respiratory syncytial virus infection.
Biochem Biophys Res Commun — Identification of nucleolin as a cellular receptor for human respiratory syncytial virus. Nat Med 17 — Identification of cellular proteins that interact with Newcastle disease virus and human respiratory syncytial virus by a two-dimensional virus overlay protein binding assay VOPBA.
Virus Res — Krusat T, Streckert HJ. Heparin-dependent attachment of respiratory syncytial virus RSV to host cells. Arch Virol — Human respiratory syncytial virus Memphis 37 grown in HEp-2 cells causes more severe disease in lambs than virus grown in Vero cells. Viruses 5 — Multiple glycosylated forms of the respiratory syncytial virus fusion protein are expressed in virus-infected cells. J Gen Virol 83 — Respiratory syncytial virus grown in Vero cells contains a truncated attachment protein that alters its infectivity and dependence on glycosaminoglycans.
J Virol 83 — Infection of ciliated cells by human parainfluenza virus type 3 in an in vitro model of human airway epithelium. Progress in understanding and controlling respiratory syncytial virus: still crazy after all these years.
CX3CR1 is expressed in differentiated human ciliated airway cells and co-localizes with respiratory syncytial virus on cilia in a G protein-dependent manner. CX3CR1 is an important surface molecule for respiratory syncytial virus infection in human airway epithelial cells.
J Gen Virol 96 — Pfeifle J, Anderer FA. Isolation and characterization of phosphoprotein pp from simian virus transformed mouse fibroblasts. Biochim Biophys Acta — Respiratory syncytial virus receptor expression in the mouse and viral tropism.
Histol Histopathol 30 — Cell-surface nucleolin acts as a central mediator for carcinogenic, anti-carcinogenic, and disease-related ligands. J Cancer Res Clin Oncol — Hospitalization attributable to influenza and other viral respiratory illnesses in Canadian children. Pediatr Infect Dis J 25 — Thurlbeck WM. Postnatal human lung growth.
Thorax 37 — Surface expressed nucleolin is constantly induced in tumor cells to mediate calcium-dependent ligand internalization. PLoS One 5 :e Comparison of DNA sequences with protein sequences.
Genomics 46 — Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody. Science — Host cell entry of respiratory syncytial virus involves macropinocytosis followed by proteolytic activation of the F protein.
PLoS Pathog 9 :e Cholesterol-rich microdomains as docking platforms for respiratory syncytial virus in normal human bronchial epithelial cells. J Virol 86 — Hughson FM. Structural characterization of viral fusion proteins. Curr Biol 5 — Molecular mechanisms and forces involved in the adhesion and fusion of amphiphilic bilayers. Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus. Structure of respiratory syncytial virus fusion glycoprotein in the postfusion conformation reveals preservation of neutralizing epitopes.
J Virol 85 — Respiratory syncytial virus inhibitor AZ differentially inhibits different polymerase activities at the promoter. J Virol 89 — Activity of oral ALS in a respiratory syncytial virus challenge study. Evidence that the respiratory syncytial virus polymerase complex associates with lipid rafts in virus-infected cells: a proteomic analysis. Virology — Interactome analysis of the human respiratory syncytial virus RNA polymerase complex identifies protein chaperones as important cofactors that promote L-protein stability and RNA synthesis.
Protein analysis of purified respiratory syncytial virus particles reveals an important role for heat shock protein 90 in virus particle assembly. Mol Cell Proteomics 9 — Mapping the transcription and replication promoters of respiratory syncytial virus. J Virol 76 — Roles of the respiratory syncytial virus trailer region: effects of mutations on genome production and stress granule formation. Functional analysis of the genomic and antigenomic promoters of human respiratory syncytial virus.
J Virol 74 — Transcriptional mapping of human respiratory syncytial virus. J Virol 52 — Effects of mutations in the gene-start and gene-end sequence motifs on transcription of monocistronic and dicistronic minigenomes of respiratory syncytial virus. J Virol 70 — Bermingham A, Collins PL. The M protein of human respiratory syncytial virus is a regulatory factor involved in the balance between RNA replication and transcription.
Cowton VM, Fearns R. Evidence that the polymerase of respiratory syncytial virus initiates RNA replication in a nontemplated fashion. Noton SL, Fearns R. The first two nucleotides of the respiratory syncytial virus antigenome RNA replication product can be selected independently of the promoter terminus.
RNA 17 — The respiratory syncytial virus polymerase has multiple RNA synthesis activities at the promoter. PLoS Pathog 8 :e Respiratory syncytial virus polymerase can initiate transcription from position 3 of the leader promoter. J Virol 87 — Factors affecting de novo RNA synthesis and back-priming by the respiratory syncytial virus polymerase.
Crystal structure of a nucleocapsid-like nucleoprotein-RNA complex of respiratory syncytial virus. Single molecule-sensitive probes for imaging RNA in live cells. Nat Methods 6 — RNA replication by a respiratory syncytial virus RNA analog does not obey the rule of six and retains a nonviral trinucleotide extension at the leader end.
Morphogenesis of respiratory syncytial virus in a green monkey kidney cell line Vero. J Virol 6 — Intracellular localization of human respiratory syncytial virus L protein. Cytoplasmic inclusions of respiratory syncytial virus-infected cells: formation of inclusion bodies in transfected cells that coexpress the nucleoprotein, the phosphoprotein, and the 22K protein.
Respiratory syncytial virus induces host RNA stress granules to facilitate viral replication. Evidence for an association between heat shock protein 70 and the respiratory syncytial virus polymerase complex within lipid-raft membranes during virus infection.
J Virol 82 — Nat Cell Biol 10 — Activation of protein kinase R is required for induction of stress granules by respiratory syncytial virus but dispensable for viral replication. Respiratory syncytial virus limits alpha subunit of eukaryotic translation initiation factor 2 eIF2alpha phosphorylation to maintain translation and viral replication.
J Biol Chem — Antiviral innate immunity and stress granule responses. Trends Immunol 35 — Montero H, Trujillo-Alonso V. Stress granules in the viral replication cycle. Viruses 3 — EMBO J 21 — Endoplasmic reticulum stress influences bronchial asthma pathogenesis by modulating nuclear factor kappaB activation.
J Allergy Clin Immunol — The relationship between respiratory viral loads and diagnosis in children presenting to a pediatric hospital emergency department. Pediatr Infect Dis J 30 :e18—e Viral load drives disease in humans experimentally infected with respiratory syncytial virus. Bronchoalveolar lavage cellularity in infants with severe respiratory syncytial virus bronchiolitis. Arch Dis Child 88 —
0コメント